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Investigation of single and synergic effects of NLRC5 and PD-L1 variants on the risk of colorectal cancer
Constitutive activation of interferon signaling pathways has been reported in colorectal cancer (CRC), leading to a strong CD8(+) T cell response through stimulation of NLRC5 expression. Primed CD8(+) T cell expansion, however, may be negatively regulated by PD-L1 expression. Additionally, aberrant...
Zapisane w:
| Wydane w: | PLoS One |
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| Główni autorzy: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2018
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800657/ https://ncbi.nlm.nih.gov/pubmed/29408916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192385 |
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