Epistatic effect of TLR3 and cGAS‐STING‐IKKε‐TBK1‐IFN signaling variants on colorectal cancer risk

OBJECTIVE: The TLR3/cGAS‐STING‐IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in these genes on the risk of sporadic colorectal cancer (CR...

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Detalhes bibliográficos
Publicado no:Cancer Med
Main Authors: Catalano, Calogerina, da Silva Filho, Miguel Inacio, Frank, Christoph, Lu, Shun, Jiraskova, Katerina, Vymetalkova, Veronika, Levy, Miroslav, Liska, Vaclav, Vycital, Ondrej, Naccarati, Alessio, Vodickova, Ludmila, Hemminki, Kari, Vodicka, Pavel, Weber, Alexander N. R., Försti, Asta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Cancer Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7013077/
https://ncbi.nlm.nih.gov/pubmed/31869529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.2804
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