Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia

BACKGROUND: Genetic testing for BRCA1 and BRCA2 is offered typically to selected women based on age of onset and family history of cancer. However, current internationally accepted genetic testing referral guidelines are built mostly on data from cancer genetics clinics in women of European descent....

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Publicado en:J Med Genet
Autores principales: Wen, Wei Xiong, Allen, Jamie, Lai, Kah Nyin, Mariapun, Shivaani, Hasan, Siti Norhidayu, Ng, Pei Sze, Lee, Daphne Shin-Chi, Lee, Sheau Yee, Yoon, Sook-Yee, Lim, Joanna, Lau, Shao Yan, Decker, Brennan, Pooley, Karen, Dorling, Leila, Luccarini, Craig, Baynes, Caroline, Conroy, Don M, Harrington, Patricia, Simard, Jacques, Yip, Cheng Har, Mohd Taib, Nur Aishah, Ho, Weang Kee, Antoniou, Antonis C, Dunning, Alison M, Easton, Douglas F, Teo, Soo Hwang
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2018
Materias:
Cancer Genetics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800345/
https://ncbi.nlm.nih.gov/pubmed/28993434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2017-104947
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