Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia

BACKGROUND: Genetic testing for BRCA1 and BRCA2 is offered typically to selected women based on age of onset and family history of cancer. However, current internationally accepted genetic testing referral guidelines are built mostly on data from cancer genetics clinics in women of European descent....

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Pubblicato in:J Med Genet
Autori principali: Wen, Wei Xiong, Allen, Jamie, Lai, Kah Nyin, Mariapun, Shivaani, Hasan, Siti Norhidayu, Ng, Pei Sze, Lee, Daphne Shin-Chi, Lee, Sheau Yee, Yoon, Sook-Yee, Lim, Joanna, Lau, Shao Yan, Decker, Brennan, Pooley, Karen, Dorling, Leila, Luccarini, Craig, Baynes, Caroline, Conroy, Don M, Harrington, Patricia, Simard, Jacques, Yip, Cheng Har, Mohd Taib, Nur Aishah, Ho, Weang Kee, Antoniou, Antonis C, Dunning, Alison M, Easton, Douglas F, Teo, Soo Hwang
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMJ Publishing Group 2018
Soggetti:
Cancer Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800345/
https://ncbi.nlm.nih.gov/pubmed/28993434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2017-104947
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