Inherited mutations in BRCA1 and BRCA2 in an unselected multiethnic cohort of Asian patients with breast cancer and healthy controls from Malaysia

BACKGROUND: Genetic testing for BRCA1 and BRCA2 is offered typically to selected women based on age of onset and family history of cancer. However, current internationally accepted genetic testing referral guidelines are built mostly on data from cancer genetics clinics in women of European descent....

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Vydáno v:J Med Genet
Hlavní autoři: Wen, Wei Xiong, Allen, Jamie, Lai, Kah Nyin, Mariapun, Shivaani, Hasan, Siti Norhidayu, Ng, Pei Sze, Lee, Daphne Shin-Chi, Lee, Sheau Yee, Yoon, Sook-Yee, Lim, Joanna, Lau, Shao Yan, Decker, Brennan, Pooley, Karen, Dorling, Leila, Luccarini, Craig, Baynes, Caroline, Conroy, Don M, Harrington, Patricia, Simard, Jacques, Yip, Cheng Har, Mohd Taib, Nur Aishah, Ho, Weang Kee, Antoniou, Antonis C, Dunning, Alison M, Easton, Douglas F, Teo, Soo Hwang
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2018
Témata:
Cancer Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800345/
https://ncbi.nlm.nih.gov/pubmed/28993434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2017-104947
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