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The Adhesion G-Protein-Coupled Receptor, GPR56/ADGRG1, Inhibits Cell–Extracellular Matrix Signaling to Prevent Metastatic Melanoma Growth

Metastatic growth is considered a rate-limiting step in cancer progression, and upregulation of extracellular matrix (ECM) deposition and cell–ECM signaling are major drivers of this process. Mechanisms to reverse ECM upregulation in cancer could potentially facilitate its prevention and treatment b...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Millar, Michelle W., Corson, Nancy, Xu, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799216/
https://ncbi.nlm.nih.gov/pubmed/29450192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00008
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