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The Adhesion G-Protein-Coupled Receptor, GPR56/ADGRG1, Inhibits Cell–Extracellular Matrix Signaling to Prevent Metastatic Melanoma Growth

Metastatic growth is considered a rate-limiting step in cancer progression, and upregulation of extracellular matrix (ECM) deposition and cell–ECM signaling are major drivers of this process. Mechanisms to reverse ECM upregulation in cancer could potentially facilitate its prevention and treatment b...

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Detalles Bibliográficos
Publicado en:Front Oncol
Autores principales: Millar, Michelle W., Corson, Nancy, Xu, Lei
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799216/
https://ncbi.nlm.nih.gov/pubmed/29450192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00008
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