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The Adhesion G-Protein-Coupled Receptor, GPR56/ADGRG1, Inhibits Cell–Extracellular Matrix Signaling to Prevent Metastatic Melanoma Growth

Metastatic growth is considered a rate-limiting step in cancer progression, and upregulation of extracellular matrix (ECM) deposition and cell–ECM signaling are major drivers of this process. Mechanisms to reverse ECM upregulation in cancer could potentially facilitate its prevention and treatment b...

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Bibliografske podrobnosti
izdano v:Front Oncol
Main Authors: Millar, Michelle W., Corson, Nancy, Xu, Lei
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5799216/
https://ncbi.nlm.nih.gov/pubmed/29450192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00008
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