Truncated forms of U2 snRNA (U2-tfs) are shunted toward a novel uridylylation pathway that differs from the degradation pathway for U1-tfs

During the biogenesis of U1 small nuclear ribonucleoprotein, a small population of U1 snRNA molecules acquires an extra methylation at the first transcribed nucleotide and a nucleolytic cleavage to remove the 3′ structured region including the Sm protein–binding site and stem-loop 4. These modificat...

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Publicado en:RNA Biol
Autores principales: Ishikawa, Hideaki, Nobe, Yuko, Izumikawa, Keiichi, Taoka, Masato, Yamauchi, Yoshio, Nakayama, Hiroshi, Simpson, Richard J, Isobe, Toshiaki, Takahash, Nobuhiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2017
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798949/
https://ncbi.nlm.nih.gov/pubmed/29168419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2017.1408766
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