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Effect of beta-agonists on LAM progression and treatment

Lymphangioleiomyomatosis (LAM), a rare disease of women, is associated with cystic lung destruction resulting from the proliferation of abnormal smooth muscle-like LAM cells with mutations in the tuberous sclerosis complex (TSC) genes TSC1 and/or TSC2. The mutant genes and encoded proteins are respo...

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Bibliographische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Le, Kang, Steagall, Wendy K., Stylianou, Mario, Pacheco-Rodriguez, Gustavo, Darling, Thomas N., Vaughan, Martha, Moss, Joel
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798385/
https://ncbi.nlm.nih.gov/pubmed/29339522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1719960115
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