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The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models

Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, affecting lungs, kidneys, and lymphatics. It is caused by the proliferation of abnormal smooth muscle–like LAM cells, with mutations and loss of heterozygosity in the TSC1 or, more frequently, TSC2 genes. Isolated pulmonary LAM cells...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Steagall, Wendy K., Pacheco-Rodriguez, Gustavo, Darling, Thomas N., Torre, Olga, Harari, Sergio, Moss, Joel
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002654/
https://ncbi.nlm.nih.gov/pubmed/29406787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0403TR
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