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The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models

Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, affecting lungs, kidneys, and lymphatics. It is caused by the proliferation of abnormal smooth muscle–like LAM cells, with mutations and loss of heterozygosity in the TSC1 or, more frequently, TSC2 genes. Isolated pulmonary LAM cells...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Steagall, Wendy K., Pacheco-Rodriguez, Gustavo, Darling, Thomas N., Torre, Olga, Harari, Sergio, Moss, Joel
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002654/
https://ncbi.nlm.nih.gov/pubmed/29406787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0403TR
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