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The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models

Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, affecting lungs, kidneys, and lymphatics. It is caused by the proliferation of abnormal smooth muscle–like LAM cells, with mutations and loss of heterozygosity in the TSC1 or, more frequently, TSC2 genes. Isolated pulmonary LAM cells...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: Steagall, Wendy K., Pacheco-Rodriguez, Gustavo, Darling, Thomas N., Torre, Olga, Harari, Sergio, Moss, Joel
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002654/
https://ncbi.nlm.nih.gov/pubmed/29406787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0403TR
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