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The Lymphangioleiomyomatosis Lung Cell and Its Human Cell Models
Lymphangioleiomyomatosis (LAM) is a multisystem disease of women, affecting lungs, kidneys, and lymphatics. It is caused by the proliferation of abnormal smooth muscle–like LAM cells, with mutations and loss of heterozygosity in the TSC1 or, more frequently, TSC2 genes. Isolated pulmonary LAM cells...
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Publicado no: | Am J Respir Cell Mol Biol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Thoracic Society
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002654/ https://ncbi.nlm.nih.gov/pubmed/29406787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0403TR |
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