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Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function
Recent advances have identified a new paradigm for cerebral malaria pathogenesis in which endothelial protein C receptor (EPCR) is a major host receptor for sequestration of Plasmodium falciparum-infected erythrocytes (IEs) in the brain and other vital organs. The parasite adhesins that bind EPCR ar...
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| Udgivet i: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5798336/ https://ncbi.nlm.nih.gov/pubmed/29339517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712879115 |
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