Linking EPCR-binding PfEMP1 to brain swelling in pediatric cerebral malaria

Brain swelling is the major predictor of mortality in pediatric cerebral malaria (CM). However, the mechanisms leading to swelling remain poorly defined. Here, we combined neuroimaging, parasite transcript profiling, and laboratory blood profiles to develop machine learning models of malarial retino...

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Bibliographic Details
Published in:Cell Host Microbe
Main Authors: Kessler, Anne, Dankwa, Selasi, Bernabeu, Maria, Harawa, Visopo, Danziger, Samuel A., Duffy, Fergal, Kampondeni, Sam D., Potchen, Michael J., Dambrauskas, Nicholas, Vigdorovich, Vladimir, Oliver, Brian G., Hochman, Sarah E., Mowrey, Wenzhu B., MacCormick, Ian J. C., Mandala, Wilson L., Rogerson, Stephen J., Sather, D. Noah, Aitchison, John D., Taylor, Terrie E., Seydel, Karl B., Smith, Joseph D., Kim, Kami
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783720/
https://ncbi.nlm.nih.gov/pubmed/29107642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.09.009
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