Linking EPCR-binding PfEMP1 to brain swelling in pediatric cerebral malaria

Brain swelling is the major predictor of mortality in pediatric cerebral malaria (CM). However, the mechanisms leading to swelling remain poorly defined. Here, we combined neuroimaging, parasite transcript profiling, and laboratory blood profiles to develop machine learning models of malarial retino...

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Bibliografske podrobnosti
izdano v:Cell Host Microbe
Main Authors: Kessler, Anne, Dankwa, Selasi, Bernabeu, Maria, Harawa, Visopo, Danziger, Samuel A., Duffy, Fergal, Kampondeni, Sam D., Potchen, Michael J., Dambrauskas, Nicholas, Vigdorovich, Vladimir, Oliver, Brian G., Hochman, Sarah E., Mowrey, Wenzhu B., MacCormick, Ian J. C., Mandala, Wilson L., Rogerson, Stephen J., Sather, D. Noah, Aitchison, John D., Taylor, Terrie E., Seydel, Karl B., Smith, Joseph D., Kim, Kami
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783720/
https://ncbi.nlm.nih.gov/pubmed/29107642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.09.009
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