Identification of the minimal binding region of a Plasmodium falciparum IgM binding PfEMP1 domain

Binding of host immunoglobulin is a common immune evasion mechanism demonstrated by microbial pathogens. Previous work showed that the malaria parasite Plasmodium falciparum binds the Fc-region of human IgM molecules, resulting in a coating of IgM on the surface of infected erythrocytes. IgM binding...

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Detalhes bibliográficos
Publicado no:Mol Biochem Parasitol
Main Authors: Semblat, Jean-Philippe, Ghumra, Ashfaq, Czajkowsky, Daniel M., Wallis, Russell, Mitchell, Daniel A., Raza, Ahmed, Rowe, J.Alexandra
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier/North-Holland Biomedical Press 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4539346/
https://ncbi.nlm.nih.gov/pubmed/26094597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molbiopara.2015.06.001
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