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Investigating the Host Binding Signature on the Plasmodium falciparum PfEMP1 Protein Family

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family plays a central role in antigenic variation and cytoadhesion of P. falciparum infected erythrocytes. PfEMP1 proteins/var genes are classified into three main subfamilies (UpsA, UpsB, and UpsC) that are hypothesized to have diff...

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Detalhes bibliográficos
Main Authors: Janes, Joel H., Wang, Christopher P., Levin-Edens, Emily, Vigan-Womas, Inès, Guillotte, Micheline, Melcher, Martin, Mercereau-Puijalon, Odile, Smith, Joseph D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3088720/
https://ncbi.nlm.nih.gov/pubmed/21573138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002032
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