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Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin

Clostridium difficile TcdB (2366 amino acid residues) is an intracellular bacterial toxin that binds to cells and enters the cytosol where it glucosylates small GTPases. In the current study, we examined a putative cell entry region of TcdB (amino acid residues 1753–1851) for short sequences that fu...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Larabee, Jason L., Hauck, Garrett D., Ballard, Jimmy D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798309/
https://ncbi.nlm.nih.gov/pubmed/29247010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.815373
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