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Amino Acid Differences in the 1753-to-1851 Region of TcdB Influence Variations in TcdB1 and TcdB2 Cell Entry

Clostridium difficile TcdB2 enters cells with a higher efficiency than TcdB1 and exhibits an overall higher level of toxicity. However, the TcdB2-specific sequences that account for more efficient cell entry have not been reported. In this study, we examined the contribution of carboxy-terminal sequ...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Hunt, Jonathan J., Larabee, Jason L., Ballard, Jimmy D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5541160/
https://ncbi.nlm.nih.gov/pubmed/28776043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00268-17
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