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Synthesis, characterization and in vitro release performance of the pegylated valnemulin prodrug
Valnemulin, successfully developed by Sandoz in 1984, is a new generation derivative of pleuromutilin related to tiamulin. Valnemulin has low water-solubility, a short half-life period, low bioavailability, and instability. The application of valnemulin was restricted. Therefore, finding a more mode...
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| Pubblicato in: | J Vet Med Sci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Japanese Society of Veterinary Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5797878/ https://ncbi.nlm.nih.gov/pubmed/29187697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.17-0434 |
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