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Synthesis and In Vitro Evaluation of Potential Sustained Release Prodrugs via Targeting ASBT
The objective was to synthesize prodrugs of niacin and ketoprofen that target the human apical sodium-dependent bile acid transporter (ASBT) and potentially allow for prolonged drug release. Each drug was conjugated to the naturally occurring bile acid chenodeoxycholic acid (CDCA) using lysine as a...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912288/ https://ncbi.nlm.nih.gov/pubmed/20600720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.06.039 |
| Etiketak: |
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