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From Synthesis to Characterization of Site-Selective PEGylated Proteins

Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for the improvement of its pharmacokinetic and pharmacological properties, as well as the reduction in reactogenicity and related side effects. This technique named PEGylation has been successfully employed in se...

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Bibliografski detalji
Izdano u:Front Pharmacol
Glavni autori: Belén, Lisandra Herrera, Rangel-Yagui, Carlota de Oliveira, Beltrán Lissabet, Jorge F., Effer, Brian, Lee-Estevez, Manuel, Pessoa, Adalberto, Castillo, Rodrigo L., Farías, Jorge G.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930235/
https://ncbi.nlm.nih.gov/pubmed/31920645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01450
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