From Synthesis to Characterization of Site-Selective PEGylated Proteins

Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for the improvement of its pharmacokinetic and pharmacological properties, as well as the reduction in reactogenicity and related side effects. This technique named PEGylation has been successfully employed in se...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Front Pharmacol
Autori principali: Belén, Lisandra Herrera, Rangel-Yagui, Carlota de Oliveira, Beltrán Lissabet, Jorge F., Effer, Brian, Lee-Estevez, Manuel, Pessoa, Adalberto, Castillo, Rodrigo L., Farías, Jorge G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930235/
https://ncbi.nlm.nih.gov/pubmed/31920645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01450
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