From Synthesis to Characterization of Site-Selective PEGylated Proteins

Covalent attachment of therapeutic proteins to polyethylene glycol (PEG) is widely used for the improvement of its pharmacokinetic and pharmacological properties, as well as the reduction in reactogenicity and related side effects. This technique named PEGylation has been successfully employed in se...

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Опубликовано в: :Front Pharmacol
Главные авторы: Belén, Lisandra Herrera, Rangel-Yagui, Carlota de Oliveira, Beltrán Lissabet, Jorge F., Effer, Brian, Lee-Estevez, Manuel, Pessoa, Adalberto, Castillo, Rodrigo L., Farías, Jorge G.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6930235/
https://ncbi.nlm.nih.gov/pubmed/31920645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01450
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