TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles

Extracellular vesicles (EV) can modulate the responses of cells to toll-like receptor (TLR) ligation; conversely, TLR ligands such as double-stranded RNA (dsRNA) can enhance the release of EV and influence of the composition and functions of EV cargos. Inflamed synovial joints in rheumatoid arthriti...

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Publicat a:Front Immunol
Autors principals: Frank-Bertoncelj, Mojca, Pisetsky, David S., Kolling, Christoph, Michel, Beat A., Gay, Renate E., Jüngel, Astrid, Gay, Steffen
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797482/
https://ncbi.nlm.nih.gov/pubmed/29434584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00028
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