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MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts
BACKGROUND: The DNA of rheumatoid arthritis synovial fibroblasts (RASF) is globally hypomethylated; this contributes to an aggressive behaviour. In an attempt to remethylate these cells, we supplemented with methyl donors. We investigated the possible interference of microRNAs (miRs). MATERIAL AND M...
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| Published in: | RMD Open |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMJ Publishing Group
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073550/ https://ncbi.nlm.nih.gov/pubmed/27843576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000299 |
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