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MicroRNAs interfere with DNA methylation in rheumatoid arthritis synovial fibroblasts

BACKGROUND: The DNA of rheumatoid arthritis synovial fibroblasts (RASF) is globally hypomethylated; this contributes to an aggressive behaviour. In an attempt to remethylate these cells, we supplemented with methyl donors. We investigated the possible interference of microRNAs (miRs). MATERIAL AND M...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:RMD Open
मुख्य लेखकों: Gaur, Niharika, Karouzakis, Emmanuel, Glück, Selene, Bagdonas, Edvardas, Jüngel, Astrid, Michel, Beat A, Gay, Renate E, Gay, Steffen, Frank-Bertoncelj, Mojca, Neidhart, Michel
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BMJ Publishing Group 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073550/
https://ncbi.nlm.nih.gov/pubmed/27843576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000299
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