Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions

A number of human diseases, such as arthritis and atherosclerosis, include characteristic pathology in specific anatomical locations. Here we show transcriptomic differences in synovial fibroblasts from different joint locations and that HOX gene signatures reflect the joint-specific origins of mous...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Frank-Bertoncelj, Mojca, Trenkmann, Michelle, Klein, Kerstin, Karouzakis, Emmanuel, Rehrauer, Hubert, Bratus, Anna, Kolling, Christoph, Armaka, Maria, Filer, Andrew, Michel, Beat A., Gay, Renate E., Buckley, Christopher D., Kollias, George, Gay, Steffen, Ospelt, Caroline
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5376654/
https://ncbi.nlm.nih.gov/pubmed/28332497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14852
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados