PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression

Programmed death ligand (PD-L1) expression was associated with tumor immune escape and subsequent poor prognosis in non-small cell lung cancer (NSCLC). This expression was higher in patients with EGFR-mutated NSCLC tumors than in those with EGFR-wild-type (WT) NSCLC tumors. We therefore hypothesized...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Tung, Jai-Nien, Lin, Po-Lin, Wang, Yao-Chen, Wu, De-Wei, Chen, Chi-Yi, Lee, Huei
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797002/
https://ncbi.nlm.nih.gov/pubmed/29435131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23161
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