Mutant p53 confers chemoresistance in non-small cell lung cancer by upregulating Nrf2

Nrf2 is a key transcription factor for genes coding for antioxidants, detoxification enzymes, and multiple drug resistance and it also confers resistance to anticancer drugs. Here, we hypothesized that mutant p53 could upregulate Nrf2 expression at the transcriptional level, thereby conferring cispl...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Tung, Min-Che, Lin, Po-Lin, Wang, Yao-Chen, He, Tsung-Ying, Lee, Ming-Ching, Yeh, Sauh-Der, Chen, Chih-Yi, Lee, Huei
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747182/
https://ncbi.nlm.nih.gov/pubmed/26497680
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky