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PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2

Nuclear Nrf2 (nNrf2) binding to the antioxidant response element may promote chemoresistance in colorectal cancer. However, the shuttling of Nrf2 between cytoplasm and nucleus in colon cancer cells has revealed the possibility that cytoplasmic location of Nrf2 (cNrf2) may play a specific role in che...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Cheng, Ya-Min, Lin, Po-Lin, Wu, De-Wei, Wang, Lee, Huang, Chi-Chou, Lee, Huei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995171/
https://ncbi.nlm.nih.gov/pubmed/29899863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25254
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