PSMD4 is a novel therapeutic target in chemoresistant colorectal cancer activated by cytoplasmic localization of Nrf2

Nuclear Nrf2 (nNrf2) binding to the antioxidant response element may promote chemoresistance in colorectal cancer. However, the shuttling of Nrf2 between cytoplasm and nucleus in colon cancer cells has revealed the possibility that cytoplasmic location of Nrf2 (cNrf2) may play a specific role in che...

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發表在:Oncotarget
Main Authors: Cheng, Ya-Min, Lin, Po-Lin, Wu, De-Wei, Wang, Lee, Huang, Chi-Chou, Lee, Huei
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2018
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995171/
https://ncbi.nlm.nih.gov/pubmed/29899863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25254
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