Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2

MicroRNA-184 suppresses cell growth and survival via targeting c-Myc and Bcl- 2. We recently reported that miR-184 promotes tumor progression in non-small cell lung cancer via targeting CDC25A and c-Myc. We here hypothesized that miR-184 could be down-regulated by E6 oncoprotein to confer cisplatin...

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Publicat a:Oncotarget
Autors principals: Tung, Min-Che, Lin, Po-Lin, Cheng, Ya-Wen, Wu, De-Wei, Yeh, Sauh-Der, Chen, Chi-Yi, Lee, Huei
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5078019/
https://ncbi.nlm.nih.gov/pubmed/27083050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8708
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