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Functional analysis of the C. elegans cyld-1 gene reveals extensive similarity with its human homolog

The human cylindromatosis tumor suppressor (HsCyld) has attracted extensive attention due to its association with the development of multiple types of cancer. HsCyld encodes a deubiquitinating enzyme (HsCYLD) with a broad range of functions that include the regulation of several cell growth, differe...

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Bibliographic Details
Published in:PLoS One
Main Authors: Hadweh, Paul, Chaitoglou, Iro, Gravato-Nobre, Maria Joao, Ligoxygakis, Petros, Mosialos, George, Hatzivassiliou, Eudoxia
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796713/
https://ncbi.nlm.nih.gov/pubmed/29394249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191864
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