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Induction of Apoptosis by Rewiring the Signal Transduction of Epstein-Barr Virus Oncoprotein LMP1 toward Caspase Activation

The Epstein-Barr virus latent membrane protein 1 (LMP1) is an oncoprotein which mimics activated tumor necrosis factor receptor family members. Here we demonstrate the principle that an inducible association of the LMP1 cytoplasmic carboxyl terminus with caspase-8 by a heterodimerizing agent causes...

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Detalhes bibliográficos
Main Authors: Hatzivassiliou, Eudoxia G., Tsichritzis, Theodore, Mosialos, George
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1069534/
https://ncbi.nlm.nih.gov/pubmed/15795305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.8.5215-5219.2005
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