Functional analysis of the C. elegans cyld-1 gene reveals extensive similarity with its human homolog

The human cylindromatosis tumor suppressor (HsCyld) has attracted extensive attention due to its association with the development of multiple types of cancer. HsCyld encodes a deubiquitinating enzyme (HsCYLD) with a broad range of functions that include the regulation of several cell growth, differe...

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Veröffentlicht in:PLoS One
Hauptverfasser: Hadweh, Paul, Chaitoglou, Iro, Gravato-Nobre, Maria Joao, Ligoxygakis, Petros, Mosialos, George, Hatzivassiliou, Eudoxia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5796713/
https://ncbi.nlm.nih.gov/pubmed/29394249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191864
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