The Tumor Suppressor CYLD Inhibits Mammary Epithelial to Mesenchymal Transition by the Coordinated Inhibition of YAP/TAZ and TGFβ Signaling

Downregulation of the cylindromatosis (CYLD) tumor suppressor has been associated with breast cancer development and progression. Here, we report a critical role for CYLD in maintaining the phenotype of mammary epithelial cells in vitro and in vivo. CYLD downregulation or inactivation induced an epi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pseftogas, Athanasios, Xanthopoulos, Konstantinos, Poutahidis, Theofilos, Ainali, Chrysanthi, Dafou, Dimitra, Panteris, Emmanuel, Kern, Joseph G., Varelas, Xaralabos, Hardas, Alexander, Gonidas, Christos, Tsingotjidou, Anastasia, Hatzivassiliou, Eudoxia, Mosialos, George
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7466024/
https://ncbi.nlm.nih.gov/pubmed/32722292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12082047
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados