Cargando...
Lapachol inhibits glycolysis in cancer cells by targeting pyruvate kinase M2
Reliance on aerobic glycolysis is one of the hallmarks of cancer. Although pyruvate kinase M2 (PKM2) is a key mediator of glycolysis in cancer cells, lack of selective agents that target PKM2 remains a challenge in exploiting metabolic pathways for cancer therapy. We report that unlike its structura...
Gardado en:
| Publicado en: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2018
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5796696/ https://ncbi.nlm.nih.gov/pubmed/29394289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191419 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|