On-target Inhibition of Tumor Fermentative Glycolysis as Visualized by Hyperpolarized Pyruvate

Many cancer cells display the Warburg effect, that is, enhanced glycolysis followed by fermentation (conversion of pyruvate to lactate). Recently, the molecular basis for these effects has started to be elucidated, and the up-regulation of the lactate dehydrogenase A (LDH-A) isoform of lactate dehyd...

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Main Authors: Seth, Pankaj, Grant, Aaron, Tang, Jian, Vinogradov, Elena, Wang, Xioaen, Lenkinski, Robert, Sukhatme, Vikas P
Formáid: Artigo
Teanga:Inglês
Foilsithe: Neoplasia Press Inc. 2011
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022429/
https://ncbi.nlm.nih.gov/pubmed/21245941
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