Loading...

Tumor-derived lactate and myeloid-derived suppressor cells: Linking metabolism to cancer immunology

Many malignant cells produce increased amounts of lactate, which promotes the development of myeloid-derived suppressor cells (MDSCs). MDSCs, lactate, and a low pH in the tumor microenvironment inhibit the function of natural killer (NK) cells and T lymphocytes, hence allowing for disease progressio...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Husain, Zaheed, Seth, Pankaj, Sukhatme, Vikas P
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3881600/
https://ncbi.nlm.nih.gov/pubmed/24404426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26383
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!