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The role of spatial organization of Ca(2+) release sites in the generation of arrhythmogenic diastolic Ca(2+) release in myocytes from failing hearts
In heart failure (HF), dysregulated cardiac ryanodine receptors (RyR2) contribute to the generation of diastolic Ca(2+) waves (DCWs), thereby predisposing adrenergically stressed failing hearts to life-threatening arrhythmias. However, the specific cellular, subcellular, and molecular defects that a...
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| Izdano u: | Basic Res Cardiol |
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| Glavni autori: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5796415/ https://ncbi.nlm.nih.gov/pubmed/28612155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00395-017-0633-2 |
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