Shortened Ca(2+) Signaling Refractoriness Underlies Cellular Arrhythmogenesis in a Postinfarction Model of Sudden Cardiac Death

RATIONALE: Diastolic spontaneous Ca(2+) waves (DCWs) are recognized as important contributors to triggered arrhythmias. DCWs are thought to arise when [Ca(2+)] in sarcoplasmic reticulum ([Ca(2+)](SR)) reaches a certain threshold level, which might be reduced in cardiac disease as a consequence of se...

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Hlavní autoři: Belevych, Andriy E., Terentyev, Dmitry, Terentyeva, Radmila, Ho, Hsiang-Ting, Gyorke, Inna, Bonilla, Ingrid M., Carnes, Cynthia A., Billman, George E., Györke, Sandor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4068617/
https://ncbi.nlm.nih.gov/pubmed/22223353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.260455
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