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Neuronal Na(+) channel blockade suppresses arrhythmogenic diastolic Ca(2+) release

AIMS: Sudden death resulting from cardiac arrhythmias is the most common consequence of cardiac disease. Certain arrhythmias caused by abnormal impulse formation including catecholaminergic polymorphic ventricular tachycardia (CPVT) are associated with delayed afterdepolarizations resulting from dia...

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Detalhes bibliográficos
Publicado no:Cardiovasc Res
Main Authors: Radwański, Przemysław B., Brunello, Lucia, Veeraraghavan, Rengasayee, Ho, Hsiang-Ting, Lou, Qing, Makara, Michael A., Belevych, Andriy E., Anghelescu, Mircea, Priori, Silvia G., Volpe, Pompeo, Hund, Thomas J., Janssen, Paul M. L., Mohler, Peter J., Bridge, John H. B., Poelzing, Steven, Györke, Sándor
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375407/
https://ncbi.nlm.nih.gov/pubmed/25538156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu262
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