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Metformin protects against oxidized low density lipoprotein-induced macrophage apoptosis and inhibits lipid uptake

Oxidized low density lipoprotein (ox-LDL)-induced macrophage apoptosis contributes to the formation of atherosclerosis. Metformin, an antidiabetic drug, has been reported to attenuate lipid accumulation in macrophages. In this study, the effects of metformin on ox-LDL-induced macrophage apoptosis we...

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Détails bibliographiques
Publié dans:Exp Ther Med
Auteurs principaux: Huangfu, Ning, Wang, Yong, Cheng, Jingsong, Xu, Zhenyu, Wang, Shenghuang
Format: Artigo
Langue:Inglês
Publié: D.A. Spandidos 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5795518/
https://ncbi.nlm.nih.gov/pubmed/29456653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2018.5704
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