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High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1

Oxidized sterols consumed in the diet or formed on low-density lipoprotein (LDL) are toxic to endothelial cells and macrophages and are thought to have a central role in promoting atherogenesis. The ATP-binding cassette transporter ABCG1 was recently shown to promote efflux of cholesterol from macro...

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Hlavní autoři: Terasaka, Naoki, Wang, Nan, Yvan-Charvet, Laurent, Tall, Alan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1986618/
https://ncbi.nlm.nih.gov/pubmed/17846428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0704602104
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