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TDP43 Exacerbates Atherosclerosis Progression by Promoting Inflammation and Lipid Uptake of Macrophages

OBJECTIVE: Atherosclerosis (AS), characterized by cholesterol overloaded-macrophages accumulation and plaque formation in blood vessels, is the major cause of cardiovascular disease. Transactive response DNA-binding protein∼43 kDa (TDP43) has recently been identified as an independent driver of neur...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Huangfu, Ning, Wang, Yong, Xu, Zhenyu, Zheng, Wenyuan, Tao, Chunlan, Li, Zhenwei, Hu, Yewen, Chen, Xiaomin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8287832/
https://ncbi.nlm.nih.gov/pubmed/34291051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.687169
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