Vascular lipid accumulation, lipoprotein oxidation and macrophage lipid uptake in hypercholesterolemic zebrafish

Lipid accumulation in arteries induces vascular inflammation and atherosclerosis, the major cause of heart attack and stroke in humans. Extreme hyperlipidemia induced in mice and rabbits enables modeling many aspects of human atherosclerosis, but microscopic examination of plaques is possible only p...

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Autori principali: Stoletov, Konstantin, Fang, Longhou, Choi, Soo-Ho, Hartvigsen, Karsten, Hansen, Lotte F., Hall, Chris, Pattison, Jennifer, Juliano, Joseph, Miller, Elizabeth R., Almazan, Felicidad, Crosier, Phil, Witztum, Joseph L., Klemke, Richard L., Miller, Yury I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834250/
https://ncbi.nlm.nih.gov/pubmed/19265037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.189803
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