Development and application of a nonradioactive binding assay of oxidized low-density lipoprotein to macrophage scavenger receptors

Macrophages play a key role in atherogenesis in part through excessive uptake of oxidized LDL (OxLDL) via scavenger receptors. Binding of OxLDL to macrophages has traditionally been assessed using radiolabeled OxLDL. To allow more efficient and convenient measurements, we developed a nonradioactive...

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Bibliografiske detaljer
Main Authors: Montano, Erica N., Boullier, Agnès, Almazan, Felicidad, Binder, Christoph J., Witztum, Joseph L., Hartvigsen, Karsten
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2013
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Methods
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793625/
https://ncbi.nlm.nih.gov/pubmed/23997238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D040923
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