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Development and application of a nonradioactive binding assay of oxidized low-density lipoprotein to macrophage scavenger receptors

Macrophages play a key role in atherogenesis in part through excessive uptake of oxidized LDL (OxLDL) via scavenger receptors. Binding of OxLDL to macrophages has traditionally been assessed using radiolabeled OxLDL. To allow more efficient and convenient measurements, we developed a nonradioactive...

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Detalhes bibliográficos
Main Authors: Montano, Erica N., Boullier, Agnès, Almazan, Felicidad, Binder, Christoph J., Witztum, Joseph L., Hartvigsen, Karsten
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3793625/
https://ncbi.nlm.nih.gov/pubmed/23997238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.D040923
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