In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

Oxidative modification of LDL is an early pathological event in the development of atherosclerosis. Oxidation events such as malondialdehyde (MDA) formation may produce specific, immunogenic epitopes. Indeed, antibodies to MDA-derived epitopes are widely used in atherosclerosis research and have bee...

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Bibliografiske detaljer
Main Authors: Fang, Longhou, Green, Simone R., Baek, Ji Sun, Lee, Sang-Hak, Ellett, Felix, Deer, Elena, Lieschke, Graham J., Witztum, Joseph L., Tsimikas, Sotirios, Miller, Yury I.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2011
Fag:
Technical Advance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225997/
https://ncbi.nlm.nih.gov/pubmed/22105168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57755
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