In vivo visualization and attenuation of oxidized lipid accumulation in hypercholesterolemic zebrafish

Oxidative modification of LDL is an early pathological event in the development of atherosclerosis. Oxidation events such as malondialdehyde (MDA) formation may produce specific, immunogenic epitopes. Indeed, antibodies to MDA-derived epitopes are widely used in atherosclerosis research and have bee...

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Autors principals: Fang, Longhou, Green, Simone R., Baek, Ji Sun, Lee, Sang-Hak, Ellett, Felix, Deer, Elena, Lieschke, Graham J., Witztum, Joseph L., Tsimikas, Sotirios, Miller, Yury I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2011
Matèries:
Technical Advance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3225997/
https://ncbi.nlm.nih.gov/pubmed/22105168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57755
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