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Antitumor effects and persistence of a novel HER2 CAR T cells directed to gastric cancer in preclinical models
New immunotherapeutic approaches are urgently needed for gastric cancer due to its poor survival and unsatisfactory treatment. Here we applied the humanized chA21 scfv based chimeric antigen receptor (CAR) modified T cells approach to the HER2 overexpressing gastric cancer treatment. The chA21-4-1BB...
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Publié dans: | Am J Cancer Res |
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Auteurs principaux: | , , , , , , , , , , , |
Format: | Artigo |
Langue: | Inglês |
Publié: |
e-Century Publishing Corporation
2018
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5794725/ https://ncbi.nlm.nih.gov/pubmed/29416924 |
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