Antitumor effects and persistence of a novel HER2 CAR T cells directed to gastric cancer in preclinical models

New immunotherapeutic approaches are urgently needed for gastric cancer due to its poor survival and unsatisfactory treatment. Here we applied the humanized chA21 scfv based chimeric antigen receptor (CAR) modified T cells approach to the HER2 overexpressing gastric cancer treatment. The chA21-4-1BB...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Cancer Res
Main Authors: Han, Yali, Liu, Chuanyong, Li, Guanhua, Li, Juan, Lv, Xingyan, Shi, Huan, Liu, Jie, Liu, Shuai, Yan, Peng, Wang, Shuyun, Sun, Yuping, Sun, Meili
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2018
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794725/
https://ncbi.nlm.nih.gov/pubmed/29416924
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