Antitumor effects and persistence of a novel HER2 CAR T cells directed to gastric cancer in preclinical models

New immunotherapeutic approaches are urgently needed for gastric cancer due to its poor survival and unsatisfactory treatment. Here we applied the humanized chA21 scfv based chimeric antigen receptor (CAR) modified T cells approach to the HER2 overexpressing gastric cancer treatment. The chA21-4-1BB...

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Detalhes bibliográficos
Publicado no:Am J Cancer Res
Main Authors: Han, Yali, Liu, Chuanyong, Li, Guanhua, Li, Juan, Lv, Xingyan, Shi, Huan, Liu, Jie, Liu, Shuai, Yan, Peng, Wang, Shuyun, Sun, Yuping, Sun, Meili
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794725/
https://ncbi.nlm.nih.gov/pubmed/29416924
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