Effective and persistent antitumor activity of HER2-directed CAR-T cells against gastric cancer cells in vitro and xenotransplanted tumors in vivo

Human epidermal growth factor receptor 2 (HER2) proteins are overexpressed in a high proportion of gastric cancer (GC) cases and affect the maintenance of cancer stem cell (CSC) subpopulations, which are used as targets for the clinical treatment of patients with HER2-positive GC. Despite improvemen...

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Enregistré dans:
Détails bibliographiques
Publié dans:Protein Cell
Auteurs principaux: Song, Yanjing, Tong, Chuan, Wang, Yao, Gao, Yunhe, Dai, Hanren, Guo, Yelei, Zhao, Xudong, Wang, Yi, Wang, Zizheng, Han, Weidong, Chen, Lin
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2017
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160382/
https://ncbi.nlm.nih.gov/pubmed/28284008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-017-0384-8
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